Transfection assay: A new test system for studying mutation induction

Abstract

A new test system for the detection of mutagens and carcinogens is presented. It is based on the observation that mutations in a gene coding for a repressor protein destroy the ability of ϕ 105 phage to lysogenizeBacillus subtilis cells. A clear instead of a turbid plaque is formed. To exclude cellular influence on the reaction of a mutagen with DNA… (More)
DOI: 10.1007/BF01965191

Topics

1 Figure or Table

Cite this paper

@article{Manna2005TransfectionAA, title={Transfection assay: A new test system for studying mutation induction}, author={Sunil K Manna and Hans J. Rhaese}, journal={Experientia}, year={2005}, volume={39}, pages={530-532} }