Transepithelial transport of the fluoroquinolone ciprofloxacin by human airway epithelial Calu-3 cells.

@article{Cavet1997TransepithelialTO,
  title={Transepithelial transport of the fluoroquinolone ciprofloxacin by human airway epithelial Calu-3 cells.},
  author={Megan E. Cavet and Michael L. West and Nicholas L. Simmons},
  journal={Antimicrobial agents and chemotherapy},
  year={1997},
  volume={41 12},
  pages={2693-8}
}
Although fluoroquinolone antibiotics such as ciprofloxacin are able to gain access to lung tissue and both pleural and bronchial secretions, the characteristics of transport and cellular uptake of ciprofloxacin in human epithelial lung tissue remain obscure. We have chosen human airway epithelial (Calu-3) cells, reconstituted as functional epithelial layers… CONTINUE READING