Transepithelial transport of the bioactive tripeptide, Val-Pro-Pro, in human intestinal Caco-2 cell monolayers.

@article{Satake2002TransepithelialTO,
  title={Transepithelial transport of the bioactive tripeptide, Val-Pro-Pro, in human intestinal Caco-2 cell monolayers.},
  author={Makoto Satake and Masashi Enjoh and Yasunori Nakamura and Toshiaki Takano and Yukio Kawamura and Soichi Arai and Makoto Shimizu},
  journal={Bioscience, biotechnology, and biochemistry},
  year={2002},
  volume={66 2},
  pages={378-84}
}
Some of the food-derived tripeptides with angiotensin converting enzyme (ACE)-inhibitory activity have been reported to be hypotensive after being orally administered. The mechanism for the intestinal transport of these tripeptides was studied by using monolayer-cultured human intestinal Caco-2 cells which express many enterocyte-like functions including… CONTINUE READING