Transepithelial permeability in the rabbit pancreas.

@article{Jansen1979TransepithelialPI,
  title={Transepithelial permeability in the rabbit pancreas.},
  author={J W Jansen and Jan Joep H. H. M. De Pont and Sjoerd L. Bonting},
  journal={Biochimica et biophysica acta},
  year={1979},
  volume={551 1},
  pages={
          95-108
        }
}

The reflexion coefficient as a measure of transepithelial permeability in the isolated rabbit pancreas.

It is concluded that the isolated rabbit pancreas is highly permeable, both to electrolytes and to small non‐electrolytes, probably being more leaky than any other epithelium studied so far.

Increased phosphate efflux from acinar cell during protein secretion.

The results indicate that either the phosphate ion is excluded from paracellular shunts or that such shunts do not contribute substantially to the transpancreatic passage of molecules of this size.

The role of sodium ions in pancreatic fluid secretion in the rabbit.

These studies confirm previous findings that extracellular Na+ is essential for pancreatic fluid secretion and indicate that the monovalent cations reach the secreted fluid through a paracellular pathway.

Effects of acetylcholine and forskolin on the non-electrolyte permeability of the perfused rabbit mandibular gland

Filtration coefficients for urea, ethanediol, glycerol, erythritol and sucrose increased with acetylcholine concentration while, with the exception of Urea, the diffusive permeabilities remained virtually unchanged.

Tight junctional permeability of the resting and carbachol stimulated exocrine rabbit pancreas

Cholinergic stimulation of the exocrine pancreas increases the permeability of the acinar cell junctions to moderately large molecules such as horseradish peroxidase, which may result in an increase of the concentration of the molecule in the secreted fluid.

Pancreatic Secretion by the Anaesthetized Rabbit in Response to Secretin, Cholecystokinin, and Carbachol

Regulation of pancreatic electrolyte secretion in rabbit differs from that in dog, cat, and human, and rat, and most closely resembles the pattern observed in guinea pig.

References

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ELECTROLYTE SECRETION FROM RABBIT PANCREAS IN VITRO.

A technic has been developed permitting direct collection of undiluted rabbit pancreatic secretion in vitro without vascular perfusion, and results are incompatible with direct plasma filtration and bicarbonate-chloride exchange as the main mechanisms of pancreatic gland secretion.

The permeability of the secretin stimulated exocrine pancreas to non‐electrolytes.

It is concluded that the pancreas is more permeable than the gall‐bladder of rabbit, fish and bull frog, the proximal tubule of the kidney of rat and the small intestine of bullfrog, but is probably similar to that ofsmall intestine of guinea‐pig and man.

A Micropuncture Investigation of the Whole Tissue Mechanism of Electrolyte Secretion by the In Vitro Rabbit Pancreas

Micropuncture techniques have been used to examine electrolyte secretion by the in vitro rabbit pancreas. The concentration profiles of the major secreted ions and digestive protein and the

CELL MEMBRANE RESORPTION IN THE RAT EXOCRINE PANCREAS CELL AFTER IN VIVO STIMULATION OF THE SECRETION, AS STUDIED BY IN VITRO INCUBATION WITH EXTRACELLULAR SPACE MARKERS

Ferritin treatment in vitro showed that the infoldings and related fragmentation vesicles had ingested ferritin and could consequently be considered as being transport vehicles for redundant cell membrane in stimulated cells.

Exocrine Secretion from the isolated Rabbit Pancreas

In the work recorded here it was possible to maintain pancreatic secretion in an in vitro preparation of rabbit pancreas for 5–6 h and to demonstrate ion concentration-flow relationships similar to those found in vivo.

High conductance in an epithelial membrane not due to extracellular shunting

The study implies that the magnitude of the epithelial resistance does not determine whether an epithelium is tight or leaky, and permeability studies with polar non-electrolytes support the conclusion that the high conductance is not due to extracellular shunting.