Transepithelial exit of leucocytes: inflicting, reflecting or resolving airway inflammation?

Abstract

The passage of infiltrated tissue granulocytes across airway epithelium into airway lumen is generally considered to be a pathogenic process in asthma and chronic obstructive pulmonary disease (COPD). An alternative hypothesis is proposed here-namely that the transepithelial egression of infiltrated leucocytes acts to rid diseased airway tissues of… (More)
DOI: 10.1136/thx.2009.133363

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