Transduodenal ampullectomy for ampullary tumors

  title={Transduodenal ampullectomy for ampullary tumors},
  author={Verushka M Mansukhani and Gunjan Shailesh Desai and S. P. Mouli and Keval Shirodkar and Rajiv C. Shah and Jagannath Palepu},
  journal={Indian Journal of Gastroenterology},
Transduodenal ampullectomy (TDA) is indicated for large ampullary tumors, for presence of dysplasia on endoscopic biopsy, for poor surgical candidates for pancreaticoduodenectomy, and in cases not indicated for endoscopic ampullectomy. Retrospective review of data from 2009 to 2015 revealed 11 patients who underwent TDA. Magnetic resonance imaging cholangiopancreatography (MRI-MRCP), contrast-enhanced computed tomography (CECT) scan, side-viewing endoscopy, and endoscopic ultrasound (EUS) were… 
7 Citations
Transduodenal ampullectomy for ampullary tumors – single center experience of consecutive 26 patients
Transduodenal ampullectomy is a feasible and effective surgical procedure for the treatment of selected patients with ampullary tumors and is an alternative treatment option in cases of ampullARY tumors not amenable to endoscopic papillectomy or pancreaticoduodenectomy.
Surgical ampullectomy: A comprehensive review
It appears that suitably selected cases of ampullary tumours subjected to SA may benefit from favourable peri-operative and long-term outcomes with very low mortality and significantly long survival, hence its role in this setting warrants further clarification, while it can also be useful in the management of specific benign entities.
Study Protocol of the ESAP Study: Endoscopic Papillectomy vs. Surgical Ampullectomy vs. Pancreaticoduodenectomy for Ampullary Neoplasm—A Pancreas2000/EPC Study
The ESAP study will provide evidence for therapeutic algorithms and data for the implementation of guidelines in the treatment of different types of ampullary tumors, including recurrent, or incomplete resected lesions.
Systematic Review with Meta-Analysis: Endoscopic and Surgical Resection for Ampullary Lesions
The data indicate an increased rate of complete resection in surgical interventions accompanied with a higher risk of complications, however, studies showed various sources of bias, limited quality of data and a significant heterogeneity, particularly in EA studies.
Pancreas-preserving duodenectomy for treatment of a duodenal papillary tumor: A case report
According to the experience with a duodenal papillary tumor, compared with pancreaticoduodenectomy, the use of pancreas-preserving duodinectomy can preserve pancreatic function, maintain gastrointestinal structure and function, reduce tissue damage and complications, and render the postoperative recovery faster.


Transduodenal Resection of Peri-Ampullary Lesions
Transduodenal resection of peri-ampullary lesions appears to be a safe alternative to radical resection for benign adenomas and selected carcinoma and Intraoperative frozen section assessment is recommended in cases of potential adenocarcinoma.
Transduodenal ampullectomy provides a less invasive technique to cure early ampullary cancer
TDA could produce satisfactory clinical efficiency in patients fulfilled the following criteria simultaneously: pTis or pT1 stage, tumor size ≤ 2 cm, without lymph node metastasis, to achieve favorable outcomes.
Surgical ampullectomy: an underestimated operation in the era of endoscopy.
Local excision as a treatment for tumors of ampulla of Vater
In this series, local excision was a safe option, associated with satisfactory long-term survival rates in patients with benign lesions and in those with small(<2 cm), pT1, well differentiated ampullary tumours without nodal involvement.
Endoscopic ampullectomy: a technical review.
Endoscopic ampullectomy is a safe and efficacious therapeutic procedure for papillary adenomas in experienced endoscopist and it can avoid the need for surgical intervention.
Characteristic endoscopic ultrasound findings of ampullary lesions that predict the need for surgical excision or endoscopic ampullectomy
Endoscopic ultrasound (EUS) data were evaluated to define characteristics that yield a high sensitivity in selecting candidates for EA and found ampullary lesions found to fit the following characteristics after EUS evaluation: lesion size <2.5 cm, invasion ≤4 mm, pancreatic duct dilatation ≤3 mm, ≤T1 lesion, no lymph nodes present, and no ductal stent in place.
Role of transduodenal ampullectomy for tumors of the ampulla of Vater
Transduodenal ampullectomy can serve as an intermediate treatment option between endoscopic papillectomy and pancreaticoduodenectomy in the management of ampulla of Vater tumors.
Endoscopic papillectomy: The limits of the indication, technique and results.
Although the endoscopic papillectomy (EP) represent higher risk endoscopic interventions, it has successfully replaced surgical treatment for benign or malignant papillary tumors and should be established as the first-line therapy for ampullary adenomas.
Tumor of the ampulla of Vater: experience with local or radical resection in 171 consecutively treated patients.
In patients with villous adenoma of the ampulla, ampullectomy was an adequate surgical treatment and the prognosis after oncological resection of cancer of the Ampulla is determined by the absence of lymph node metastasis, the presence of infiltration into the pancreatic head tissue and the application of an R0 resection.