Transduction sites of vagal mechanoreceptors in the guinea pig esophagus.

@article{Zagorodnyuk2000TransductionSO,
  title={Transduction sites of vagal mechanoreceptors in the guinea pig esophagus.},
  author={Vladimir P. Zagorodnyuk and Simon J Brookes},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2000},
  volume={20 16},
  pages={6249-55}
}
Extrinsic afferent neurons play an essential role in both sensation and reflex control of visceral organs, but their specialized morphological peripheral endings have never been functionally identified. Extracellular recordings were made from fine nerve trunks running between the vagus nerve and esophagus of the guinea pig. Mechanoreceptors, which responded to esophageal distension, fired spontaneously, had low thresholds to circumferential stretch, and were slowly adapting. Calibrated von Frey… CONTINUE READING
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