Transduction of Herpesvirus saimiri-Transformed T Cells with Exogenous Genes of Interest.

Abstract

Human T cells can be transformed and expanded with herpesvirus saimiri (HVS). HVS-transformed T cells from patients have facilitated the study of a broad range of primary immunodeficiencies (PID) in which T-cell development or function is altered. However, the utility of HVS-transformed T cells for genetic studies has been limited by technical challenges in… (More)
DOI: 10.1002/cpim.15

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