Transdifferentiation in Holothurian Gut Regeneration

@article{Mashanov2005TransdifferentiationIH,
  title={Transdifferentiation in Holothurian Gut Regeneration},
  author={Vladimir S. Mashanov and Igor Yu. Dolmatov and Thomas Heinzeller},
  journal={The Biological Bulletin},
  year={2005},
  volume={209},
  pages={184 - 193}
}
It has recently been shown that the whole spectrum of cell types constituting a multicellular organism can be generated from stem cells. Our study provides an example of an alternative mechanism of tissue repair. Injection of distilled water into the coelomic cavity of the holothurian Eupentacta fraudatrix results in the loss of the whole digestive tract, except the cloaca. The new gut reforms from two separate rudiments. One rudiment appears at the anterior end of the body and extends… 

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