Transdifferentiation in Holothurian Gut Regeneration

  title={Transdifferentiation in Holothurian Gut Regeneration},
  author={V. Mashanov and I. Dolmatov and T. Heinzeller},
  journal={The Biological Bulletin},
  pages={184 - 193}
  • V. Mashanov, I. Dolmatov, T. Heinzeller
  • Published 2005
  • Biology, Medicine
  • The Biological Bulletin
  • It has recently been shown that the whole spectrum of cell types constituting a multicellular organism can be generated from stem cells. Our study provides an example of an alternative mechanism of tissue repair. Injection of distilled water into the coelomic cavity of the holothurian Eupentacta fraudatrix results in the loss of the whole digestive tract, except the cloaca. The new gut reforms from two separate rudiments. One rudiment appears at the anterior end of the body and extends… CONTINUE READING
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