Transdifferentiation: a cell and molecular reprogramming process

  title={Transdifferentiation: a cell and molecular reprogramming process},
  author={Sajjad Sisakhtnezhad and Maryam M. Matin},
  journal={Cell and Tissue Research},
Evidence has emerged recently indicating that differentiation is not entirely a one-way process, and that it is possible to convert one cell type to another, both in vitro and in vivo. This phenomenon is called transdifferentiation, and is generally defined as the stable switch of one cell type to another. Transdifferentiation plays critical roles during development and in regeneration pathways in nature. Although this phenomenon occurs rarely in nature, recent studies have been focused on… 



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