Transdermal therapeutic systems for memantine delivery. Comparison of passive and iontophoretic transport.

Abstract

Memantine is a non-competitive N-methyl-d-aspartate (NMDA) receptor antagonist used in the treatment of moderate to severe dementia including the symptoms of Alzheimer's disease (AD). It is administered orally but compliance, swallowing problems and the routine use of multiple medications in elderly AD patients means that an alternative route of… (More)
DOI: 10.1016/j.ijpharm.2016.11.038

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Cite this paper

@article{RoSancho2017TransdermalTS, title={Transdermal therapeutic systems for memantine delivery. Comparison of passive and iontophoretic transport.}, author={Sergio del R{\'i}o-Sancho and C E Serna-Jim{\'e}nez and Mar{\'i}a Sebasti{\'a}n-Morell{\'o} and Mar{\'i}a Aracely Calatayud-Pascual and Cristina Balaguer-Fern{\'a}ndez and Andr{\'e}s Femen{\'i}a-Font and Yogeshvar N. Kalia and Vanessa Merino and Alicia C L{\'o}pez-Castellano}, journal={International journal of pharmaceutics}, year={2017}, volume={517 1-2}, pages={104-111} }