Transdermal nitroglycerin patches in angina pectoris. Dose titration, duration of effect, and rapid tolerance.

@article{Thadani1986TransdermalNP,
  title={Transdermal nitroglycerin patches in angina pectoris. Dose titration, duration of effect, and rapid tolerance.},
  author={Udho Thadani and Stephan Hamilton and Ellen R Olson and Jeffrey L Anderson and W. F. Voyles and Rameshwar Prasad and Steve M. Teague},
  journal={Annals of internal medicine},
  year={1986},
  volume={105 4},
  pages={485-92}
}
The duration of effect of transdermal nitroglycerin patches was studied in 14 patients with angina pectoris. By titrating the dose to achieve specific circulatory effects, we chose a patch size that produced a consistent fall in systolic blood pressure of 10 mm Hg or greater for each patient (10 cm2 in 7 patients, 20 cm2 in 5, and 40 cm2 in 2; releasing 5… CONTINUE READING