Transdermal nicotine: single dose effects on mood, EEG, performance, and event-related potentials.

@article{Knott1999TransdermalNS,
  title={Transdermal nicotine: single dose effects on mood, EEG, performance, and event-related potentials.},
  author={Verner Knott and Maartje Bosman and Colleen Mahoney and Vadim Ilivitsky and K Quirt},
  journal={Pharmacology, biochemistry, and behavior},
  year={1999},
  volume={63 2},
  pages={253-61}
}
A 21-mg dose of nicotine was administered transdermally to 16 overnight smoking-deprived smokers in a double-blind, placebo-controlled design. Mood ratings, electroencephalography (EEG), behavioral performance and event-related potential (ERP: P300) indices of attention and information processing speed were assessed before and 4 h after placebo/nicotine treatment. Although nicotine, relative to placebo, failed to alter mood, it increased absolute and relative power indices of EEG arousal… CONTINUE READING

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