Transdermal delivery of human growth hormone via laser-generated micropores

@article{Song2017TransdermalDO,
  title={Transdermal delivery of human growth hormone via laser-generated micropores},
  author={Yang Song and Karishma Hemmady and Ashana Puri and Ajay K. Banga},
  journal={Drug Delivery and Translational Research},
  year={2017},
  volume={8},
  pages={450-460}
}
The epidermal skin barrier plays an important role in protecting underlying structures. It allows the passage of low molecular weight lipophilic molecules, but restricts the passage of hydrophilic molecules and macromolecules. The objective of this study was to investigate the feasibility of transdermal delivery of human growth hormone (hGH) through laser-microporated dermatomed porcine ear skin. The permeation of hGH was evaluated at different laser fluences and micropore densities. In vitro… CONTINUE READING
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