Transcutaneous immunization: an emerging route of immunization and potent immunostimulation strategy.

@article{Hammond2001TranscutaneousIA,
  title={Transcutaneous immunization: an emerging route of immunization and potent immunostimulation strategy.},
  author={Scott A. Hammond and Mimi Guebre-Xabier and Jinzhi Yu and Gregory M. Glenn},
  journal={Critical reviews in therapeutic drug carrier systems},
  year={2001},
  volume={18 5},
  pages={503-26}
}
Transcutaneous immunization (TCI) has emerged recently as a new method of vaccination that uses the skin. The simplicity of a patch-based immunization may obscure the potency of this strategy for immunostimulation because TCI allows the safe use of a wide variety of potent adjuvants. It is thought that these adjuvants activate Langerhans cells in the skin, which migrate to the draining lymph to orchestrate robust systemic immune responses. TCI represents a novel combination using established… CONTINUE READING

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