Transcriptomics of Maternal and Fetal Membranes Can Discriminate between Gestational-Age Matched Preterm Neonates with and without Cognitive Impairment Diagnosed at 18–24 Months

@inproceedings{Pappas2015TranscriptomicsOM,
  title={Transcriptomics of Maternal and Fetal Membranes Can Discriminate between Gestational-Age Matched Preterm Neonates with and without Cognitive Impairment Diagnosed at 18–24 Months},
  author={Athina Pappas and Tinnakorn Chaiworapongsa and Roberto Romero and Steven J Korzeniewski and Josef Misael C Cortez and Gaurav Bhatti and Nardhy Gomez-Lopez and Sonia S. Hassan and Seetha Shankaran and Adi L Tarca},
  booktitle={PloS one},
  year={2015}
}
BACKGROUND Neurocognitive impairment among children born preterm may arise from complex interactions between genes and the intra-uterine environment. OBJECTIVES (1) To characterize the transcriptomic profiles of chorioamniotic membranes in preterm neonates with and without neurocognitive impairment via microarrays and (2) to determine if neonates with neurocognitive impairment can be identified at birth. MATERIALS/METHODS A retrospective case-control study was conducted to examine the… CONTINUE READING
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