Transcriptomics and in vivo tests reveal novel mechanisms underlying endocrine disruption in an ecological sentinel, Nucella lapillus.

@article{Pascoal2013TranscriptomicsAI,
  title={Transcriptomics and in vivo tests reveal novel mechanisms underlying endocrine disruption in an ecological sentinel, Nucella lapillus.},
  author={S{\'o}nia Pascoal and Gary R. Carvalho and Olga Vasieva and Roger W. Hughes and Andrew Cossins and Yongxiang Fang and Kevin E. Ashelford and Lisa Olohan and Carlos Miguel Miguez Barroso and S{\'o}nia Mendo and Simon Creer},
  journal={Molecular ecology},
  year={2013},
  volume={22 6},
  pages={1589-608}
}
Anthropogenic endocrine disruptors now contaminate all environments globally, with concomitant deleterious effects across diverse taxa. While most studies on endocrine disruption (ED) have focused on vertebrates, the superimposition of male sexual characteristics in the female dogwhelk, Nucella lapillus (imposex), caused by organotins, provides one of the most clearcut ecological examples of anthropogenically induced ED in aquatic ecosystems. To identify the underpinning mechanisms of imposex… CONTINUE READING
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