Transcriptomic response of Listeria monocytogenes to iron limitation and Fur mutation.

  title={Transcriptomic response of Listeria monocytogenes to iron limitation and Fur mutation.},
  author={Nagender Ledala and Mrittika Sengupta and Arunachalam Muthaiyan and Brian J. Wilkinson and Radheshyam K. Jayaswal},
  journal={Applied and environmental microbiology},
  volume={76 2},
Iron is required by almost all bacteria, but concentrations above physiological levels are toxic. In bacteria, intracellular iron is regulated mostly by the ferric uptake regulator, Fur, or a similar functional protein. Iron limitation results in the regulation of a number of genes, especially those involved in iron uptake. A subset of these genes is the Fur regulon under the control of Fur. In the present study, we have identified Fur- and iron-regulated genes in Listeria monocytogenes by DNA… CONTINUE READING

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