Transcriptomic characterization of the long-term dihydrotestosterone effects in adipose tissue.

@article{Bolduc2007TranscriptomicCO,
  title={Transcriptomic characterization of the long-term dihydrotestosterone effects in adipose tissue.},
  author={Carl Bolduc and Mayumi Yoshioka and Jonny St-Amand},
  journal={Obesity},
  year={2007},
  volume={15 5},
  pages={1107-32}
}
OBJECTIVE To study the long-term transcriptomic effects of dihydrotestosterone (DHT) in adipose tissue. Fat distribution is regulated by sexual hormones. It is still unclear if androgens are promoting or reducing intra-abdominal fat accumulation. RESEARCH METHODS AND PROCEDURES Retroperitoneal adipose tissue were isolated from each group of gonadectomized (GDX) C57BL6 male mice treated with vehicle or DHT for 21 days. Serial analysis of gene expression (SAGE) was performed to generate… CONTINUE READING

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