Transcriptomic analysis of gene cascades involved in protein kinase A and C signaling in the KGN line of human ovarian granulosa tumor cells†

@article{Tremblay2017TranscriptomicAO,
  title={Transcriptomic analysis of gene cascades involved in protein kinase A and C signaling in the KGN line of human ovarian granulosa tumor cells†},
  author={Patricia G Tremblay and Marc-Andr{\'e} Sirard},
  journal={Biology of Reproduction},
  year={2017},
  volume={96},
  pages={855 - 865}
}
Abstract The developmental competence of an oocyte is its capacity to resume maturation, undergo successful fertilization, and reach the blastocyst stage. This competence is acquired through interaction with somatic cells of the follicle. Cumulus and granulosa cells support oocyte development, while the oocyte influences follicular cell growth and differentiation. Studies suggest that folliclestimulating hormone and luteinizing hormone play an essential role in oocyte competence acquisition… CONTINUE READING
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