Transcriptomic analysis of cells in response to EV71 infection and 2Apro as a trigger for apoptosis via TXNIP gene

@article{Yao2018TranscriptomicAO,
  title={Transcriptomic analysis of cells in response to EV71 infection and 2Apro as a trigger for apoptosis via TXNIP gene},
  author={Chenguang Yao and Kanghong Hu and Caili Xi and Ni Li and Yanhong Wei},
  journal={Genes & Genomics},
  year={2018},
  volume={41},
  pages={343-357}
}
BackgroundEnterovirus 71 (EV71) is the main pathogen of hand-foot-mouth disease (HFMD) and sometimes causes several neurological complications. However, the underlying mechanism of the host response to the virus infection remains unclear.ObjectiveTo reveal the cell-specific transcriptional response of cultured RD cells following infection with EV71, and better understand the molecular mechanisms of virus-host interactions.MethodsThe RD cells were infected with or without EV71 for 24 h, and then… CONTINUE READING
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