Transcriptomic analysis of Ruditapes philippinarum hemocytes reveals cytoskeleton disruption after in vitro Vibrio tapetis challenge.

@article{Brulle2012TranscriptomicAO,
  title={Transcriptomic analysis of Ruditapes philippinarum hemocytes reveals cytoskeleton disruption after in vitro Vibrio tapetis challenge.},
  author={Franck Brulle and Fanny Jeffroy and St{\'e}phanie Madec and Jean-Louis Nicolas and Christine Paillard},
  journal={Developmental and comparative immunology},
  year={2012},
  volume={38 2},
  pages={368-76}
}
The Manila clam, Ruditapes philippinarum, is an economically-important, commercial shellfish; harvests are diminished in some European waters by a pathogenic bacterium, Vibrio tapetis, that causes Brown Ring disease. To identify molecular characteristics associated with susceptibility or resistance to Brown Ring disease, Suppression Subtractive Hybridization (SSH) analyzes were performed to construct cDNA libraries enriched in up- or down-regulated transcripts from clam immune cells, hemocytes… CONTINUE READING

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