Transcriptomic analysis identified up-regulation of a solute carrier transporter and UDP glucuronosyltransferases in dogs with aggressive cutaneous mast cell tumours.

@article{Giantin2016TranscriptomicAI,
  title={Transcriptomic analysis identified up-regulation of a solute carrier transporter and UDP glucuronosyltransferases in dogs with aggressive cutaneous mast cell tumours.},
  author={Mery Giantin and Chiara Baratto and Laura Marconato and Marta Vascellari and Franco Mutinelli and Mauro Dacasto and Anna Granato},
  journal={Veterinary journal},
  year={2016},
  volume={212},
  pages={36-43}
}
Gene expression analyses have been recently used in cancer research to identify genes associated with tumorigenesis and potential prognostic markers or therapeutic targets. In the present study, the transcriptome of dogs that had died because of mast cell tumours (MCTs) was characterised to identify a fingerprint having significant influence on prognosis determination and treatment selection. A dataset (GSE50433) obtained using a commercial canine DNA microarray platform was used. The… CONTINUE READING