Transcriptomic analyses of murine resolution-phase macrophages.

@article{Stables2011TranscriptomicAO,
  title={Transcriptomic analyses of murine resolution-phase macrophages.},
  author={Melanie J Stables and Sonia Shah and E. B. Camon and Ruth C. Lovering and Justine Newson and Jonas Bystrom and Stuart Farrow and Derek W Gilroy},
  journal={Blood},
  year={2011},
  volume={118 26},
  pages={
          e192-208
        }
}
Macrophages are either classically (M1) or alternatively-activated (M2). Whereas this nomenclature was generated from monocyte-derived macrophages treated in vitro with defined cytokine stimuli, the phenotype of in vivo-derived macrophages is less understood. We completed Affymetrix-based transcriptomic analysis of macrophages from the resolution phase of a zymosan-induced peritonitis. Compared with macrophages from hyperinflamed mice possessing a pro-inflammatory nature as well as naive… CONTINUE READING

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