Transcriptomic alterations in the heart of non-obese type 2 diabetic Goto-Kakizaki rats

  title={Transcriptomic alterations in the heart of non-obese type 2 diabetic Goto-Kakizaki rats},
  author={M{\'a}rta Julianna S{\'a}rk{\"o}zy and Gergő Szűcs and Veronika Fekete and M{\'a}rton Pipicz and Katalin {\'E}der and Renata Gaspar and Andrea S{\'o}ja and Judit Pipis and P{\'e}ter Ferdinandy and Csaba Csonka and Tam{\aa}s Csont},
  booktitle={Cardiovascular diabetology},
BACKGROUND There is a spectacular rise in the global prevalence of type 2 diabetes mellitus (T2DM) due to the worldwide obesity epidemic. However, a significant proportion of T2DM patients are non-obese and they also have an increased risk of cardiovascular diseases. As the Goto-Kakizaki (GK) rat is a well-known model of non-obese T2DM, the goal of this study was to investigate the effect of non-obese T2DM on cardiac alterations of the transcriptome in GK rats. METHODS Fasting blood glucose… CONTINUE READING
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