Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells.

@article{Li2016TranscriptomicPM,
  title={Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells.},
  author={Guang Li and Adele F. Xu and Sopheak Sim and James Rush Priest and Xueying Tian and Tooba Khan and Thomas Quertermous and Bin Zhou and Philip S. Tsao and Stephen R Quake and Sean M Wu},
  journal={Developmental cell},
  year={2016},
  volume={39 4},
  pages={491-507}
}
Embryonic gene expression intricately reflects anatomical context, developmental stage, and cell type. To address whether the precise spatial origins of cardiac cells can be deduced solely from their transcriptional profiles, we established a genome-wide expression database from 118, 949, and 1,166 single murine heart cells at embryonic day 8.5 (e8.5), e9.5… CONTINUE READING