Transcriptome profiling reveals differentially expressed transcripts between the human adrenal zona fasciculata and zona reticularis.

@article{Rege2014TranscriptomePR,
  title={Transcriptome profiling reveals differentially expressed transcripts between the human adrenal zona fasciculata and zona reticularis.},
  author={Juilee Rege and Yasuhiro Nakamura and Tao Wang and Todd D Merchen and Hironobu Sasano and William E. Rainey},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2014},
  volume={99 3},
  pages={E518-27}
}
CONTEXT The human adrenal zona fasciculata (ZF) and zona reticularis (ZR) are responsible for the production of cortisol and 19-carbon steroids (often called adrenal androgens), respectively. However, the gene profiles and exact molecular mechanisms leading to the functional phenotype of the ZF and ZR are still not clearly defined. In the present study, we identified the transcripts that are differentially expressed in the ZF and ZR. OBJECTIVE The objective of the study was to compare the… CONTINUE READING
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