Transcriptome from circulating cells suggests dysregulated pathways associated with long-term recurrent events following first-time myocardial infarction.

@article{Suresh2014TranscriptomeFC,
  title={Transcriptome from circulating cells suggests dysregulated pathways associated with long-term recurrent events following first-time myocardial infarction.},
  author={Rahul Suresh and Xing Li and Anca Chiriac and Kashish Goel and Andre Terzic and Carmen M P{\'e}rez-Terzic and Timothy J. Nelson},
  journal={Journal of molecular and cellular cardiology},
  year={2014},
  volume={74},
  pages={13-21}
}
BACKGROUND Whole-genome gene expression analysis has been successfully utilized to diagnose, prognosticate, and identify potential therapeutic targets for high-risk cardiovascular diseases. However, the feasibility of this approach to identify outcome-related genes and dysregulated pathways following first-time myocardial infarction (AMI) remains unknown and may offer a novel strategy to detect affected expressome networks that predict long-term outcome. METHODS AND RESULTS Whole-genome… CONTINUE READING
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