Transcriptome changes during intestinal cell differentiation.

  title={Transcriptome changes during intestinal cell differentiation.},
  author={Mehrdad Tadjali and Jakob Benedict Seidelin and J\orgen L. Olsen and Jesper Thorvald Troelsen},
  journal={Biochimica et biophysica acta},
  volume={1589 2},
The expression of 18149 genes have been analysed during the differentiation of the human intestinal cell line Caco-2. cDNA probes from undifferentiated and differentiated Caco-2 cells were separately hybridised to EST DNAs spotted in an array on a nylon membrane. A remarkable change in the transcriptome was observed during the differentiation of the Caco-2 cells. 8762 of the 18149 genes analysed were expressed above background level in the undifferentiated Caco-2 cells, whereas only 5767 genes… CONTINUE READING


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