Transcriptome analysis of the interferon-signature defining the autoimmune process of Sjögren's syndrome.

Abstract

Sjögren's syndrome (SS) of humans and SS-like (SjS-like) diseases in mouse models are characterized by chronic immune attacks against the salivary and lacrimal glands leading to exocrine dysfunction. One characteristic of SS and SjS-like diseases repeatedly observed is a strong upregulated expression of both the type I (α/β) and type II (γ) interferons… (More)
DOI: 10.1111/j.1365-3083.2012.02749.x

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