Transcriptome analysis of neutrophils after endurance exercise reveals novel signaling mechanisms in the immune response to physiological stress.

@article{Neubauer2013TranscriptomeAO,
  title={Transcriptome analysis of neutrophils after endurance exercise reveals novel signaling mechanisms in the immune response to physiological stress.},
  author={Oliver Neubauer and S. Sabapathy and R. Lazarus and J. Jowett and B. Desbrow and J. Peake and D. Cameron-Smith and L. Haseler and K. Wagner and A. Bulmer},
  journal={Journal of applied physiology},
  year={2013},
  volume={114 12},
  pages={
          1677-88
        }
}
Neutrophils serve as an intriguing model for the study of innate immune cellular activity induced by physiological stress. We measured changes in the transcriptome of circulating neutrophils following an experimental exercise trial (EXTRI) consisting of 1 h of intense cycling immediately followed by 1 h of intense running. Blood samples were taken at baseline, 3 h, 48 h, and 96 h post-EXTRI from eight healthy, endurance-trained, male subjects. RNA was extracted from isolated neutrophils… Expand
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