Transcriptome analysis of genes and gene networks involved in aggressive behavior in mouse and zebrafish

@article{Malki2016TranscriptomeAO,
  title={Transcriptome analysis of genes and gene networks involved in aggressive behavior in mouse and zebrafish},
  author={K. Malki and E. Du Rietz and Wim E. Crusio and O. Pain and J. Paya-Cano and Rezhaw L Karadaghi and F. Sluyter and S. D. de Boer and K. Sandnabba and L. Schalkwyk and P. Asherson and M. Tosto},
  journal={American Journal of Medical Genetics Part B: Neuropsychiatric Genetics},
  year={2016},
  volume={171},
  pages={827 - 838}
}
  • K. Malki, E. Du Rietz, +9 authors M. Tosto
  • Published 2016
  • Biology, Medicine
  • American Journal of Medical Genetics Part B: Neuropsychiatric Genetics
Despite moderate heritability estimates, the molecular architecture of aggressive behavior remains poorly characterized. This study compared gene expression profiles from a genetic mouse model of aggression with zebrafish, an animal model traditionally used to study aggression. A meta‐analytic, cross‐species approach was used to identify genomic variants associated with aggressive behavior. The Rankprod algorithm was used to evaluated mRNA differences from prefrontal cortex tissues of three… Expand
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  • Biology, Medicine
  • American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics
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