Transcriptome analysis of Paracoccidioides brasiliensis cells undergoing mycelium-to-yeast transition.

  title={Transcriptome analysis of Paracoccidioides brasiliensis cells undergoing mycelium-to-yeast transition.},
  author={Luiz R. Nunes and Regina Costa de Oliveira and Daniela Batista Leite and Vivian Schmidt da Silva and Everaldo dos Reis Marques and M{\'a}rcia Eliana da Silva Ferreira and Di{\'o}genes Cust{\'o}dio Duarte Ribeiro and Luciano Angelo de Souza Bernardes and Maria Helena de Souza Goldman and Rosana Puccia and Luiz R Travassos and Wagner Luiz Batista and Marina Pasetto N{\'o}brega and Francisco G. N{\'o}brega and Ding-Yah Yang and Carlos Alberto de Bragança Pereira and Gustavo Henrique Goldman},
  journal={Eukaryotic cell},
  volume={4 12},
Paracoccidioides brasiliensis is a thermodimorphic fungus associated with paracoccidioidomycosis (PCM), a systemic mycosis prevalent in South America. In humans, infection starts by inhalation of fungal propagules, which reach the pulmonary epithelium and transform into the yeast parasitic form. Thus, the mycelium-to-yeast transition is of particular interest because conversion to yeast is essential for infection. We have used a P. brasiliensis biochip carrying sequences of 4,692 genes from… CONTINUE READING


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