Transcriptome analysis and physiology of Bifidobacterium longum NCC2705 cells under continuous culture conditions.

@article{Mozzetti2012TranscriptomeAA,
  title={Transcriptome analysis and physiology of Bifidobacterium longum NCC2705 cells under continuous culture conditions.},
  author={Valeria Mozzetti and Franck Grattepanche and D{\'e}borah Moine and Beatrice Berger and Enea Rezzonico and Fabrizio Arigoni and Christophe Lacroix},
  journal={Beneficial microbes},
  year={2012},
  volume={3 4},
  pages={261-72}
}
A central issue in the use of probiotics in food and food supplements is their sensitivity to many environmental stress factors. The resistance of probiotic cells to lethal stress can be improved by application of homologous or heterologous sub-lethal stress during culture. This screening procedure is generally performed using batch cultures. Continuous cultures could be a suitable and more efficient method to test different stress factors on one culture instead of repeating several batch… CONTINUE READING