Transcriptome analysis and molecular studies on sulfur metabolism in the human pathogenic fungus Paracoccidioides brasiliensis

@article{Ferreira2006TranscriptomeAA,
  title={Transcriptome analysis and molecular studies on sulfur metabolism in the human pathogenic fungus Paracoccidioides brasiliensis},
  author={M{\'a}rcia Eliana da Silva Ferreira and Everaldo dos Reis Marques and Iran Malavazi and Isaura P Torres and {\'A}ngela Restrepo and Luiz R. Nunes and Regina Costa de Oliveira and Maria Helena de Souza Goldman and Gustavo Henrique Goldman},
  journal={Molecular Genetics and Genomics},
  year={2006},
  volume={276},
  pages={450-463}
}
The dimorphic pathogenic fungus Paracoccidioides brasiliensis can grow as a prototroph for organic sulfur as a mycelial (non-pathogenic) form, but it is unable to assimilate inorganic sulfur as a yeast (pathogenic) form. Temperature and the inability to assimilate inorganic sulfur are the single conditions known to affect P. brasiliensis mycelium-to-yeast (M–Y) dimorphic transition. For a comprehensive evaluation of genes that have their expression modulated during the M–Y transition in… CONTINUE READING
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