Transcriptome analyses of differential gene expression in the bursa of Fabricius between Silky Fowl and White Leghorn

@inproceedings{Han2017TranscriptomeAO,
  title={Transcriptome analyses of differential gene expression in the bursa of Fabricius between Silky Fowl and White Leghorn},
  author={Deping Han and Yuanyuan Zhang and Jianfei Chen and Guoying Hua and Junying Li and Xuegong Deng and Xuemei Deng},
  booktitle={Scientific reports},
  year={2017}
}
Hyperpigmentation in Silky Fowl (SF) results in aberrant immune cell development. However, how melanocytes regulate B-cell proliferation in the bursa of Fabricius (BF) is unclear. To resolve this conundrum, we collected BFs from three-week-old SF and White Leghorn (WL) female chickens for RNA sequencing. The BF development was relatively weaker in SF than in WL. The transcriptome analyses identified 4848 differentially expressed genes, 326 long noncoding RNAs (lncRNAs), and 67 microRNAs in the… CONTINUE READING
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