Transcriptome Variability in Keratocystic Odontogenic Tumor Suggests Distinct Molecular Subtypes.

@article{Hu2016TranscriptomeVI,
  title={Transcriptome Variability in Keratocystic Odontogenic Tumor Suggests Distinct Molecular Subtypes.},
  author={Shijia Hu and Kimon Divaris and Joel S. Parker and Ricardo Padilla and Valerie A Murrah and John Timothy Wright},
  journal={Scientific reports},
  year={2016},
  volume={6},
  pages={24236}
}
Keratocystic Odontogenic Tumor (KCOT) is a locally aggressive developmental cystic neoplasm thought to arise from the odontogenic epithelium. A high recurrence rate of up to 30% has been found following conservative treatment. Aggressive tumor resection can lead to the need for extensive reconstructive surgery, resulting in significant morbidity and impacting quality of life. Most research has focused on candidate-genes with a handful of studies employing whole transcriptome approaches. There… CONTINUE READING
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