Transcriptome Sequencing Reveals the Character of Incomplete Dosage Compensation across Multiple Tissues in Flycatchers

@inproceedings{Uebbing2013TranscriptomeSR,
  title={Transcriptome Sequencing Reveals the Character of Incomplete Dosage Compensation across Multiple Tissues in Flycatchers},
  author={Severin Uebbing and Axel Kuenstner and Hannu S M{\"a}kinen and Hans Ellegren},
  booktitle={Genome biology and evolution},
  year={2013}
}
Sex chromosome divergence, which follows the cessation of recombination and degeneration of the sex-limited chromosome, can cause a reduction in expression level for sex-linked genes in the heterozygous sex, unless some mechanisms of dosage compensation develops to counter the reduction in gene dose. Because large-scale perturbations in expression levels arising from changes in gene dose might have strong deleterious effects, the evolutionary response should be strong. However, in birds and in… CONTINUE READING
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