Transcriptome Analysis of HER 2 Reveals a Molecular Connection to Fatty Acid Synthesis 1

@inproceedings{KumarSinha2002TranscriptomeAO,
  title={Transcriptome Analysis of HER 2 Reveals a Molecular Connection to Fatty Acid Synthesis 1},
  author={Chandan Kumar-Sinha and Kathleen M. Woods Ignatoski and Marc E. Lippman and Stephen P Ethier and Arul M. Chinnaiyan},
  year={2002}
}
HER2 (erbB2/neu) is a member of the erbB family of receptor tyrosine kinases and is involved in regulating the growth of several types of human carcinomas. HER2 represents a successful therapeutic target of the biotechnology era as exemplified by the drug Herceptin (trastuzumab), which has clinical activity in a subset of breast cancer patients. Using DNA microarrays, we identified a cohort of genes that are differentially regulated by HER2 in breast epithelial cells. One of the HER2-regulated… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations

Erythrocyte membrane phospholipid fatty acid concentrations and risk of colorectal adenomas: a case-control nested in the French E3N-EPIC cohort study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology • 2013

Integrated genomic and transcriptomic analysis of ductal carcinoma in situ of the breast.

Clinical cancer research : an official journal of the American Association for Cancer Research • 2008

References

Publications referenced by this paper.
Showing 1-10 of 62 references

Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2002

Similar Papers

Loading similar papers…