Transcriptomal analysis of varicella-zoster virus infection using long oligonucleotide-based microarrays.

@article{Kennedy2005TranscriptomalAO,
  title={Transcriptomal analysis of varicella-zoster virus infection using long oligonucleotide-based microarrays.},
  author={Peter G. E. Kennedy and Esther Grinfeld and Marie H. Craigon and Klemens Vierlinger and Douglas Roy and Thorsten Forster and Peter Ghazal},
  journal={The Journal of general virology},
  year={2005},
  volume={86 Pt 10},
  pages={
          2673-84
        }
}
Varicella-zoster virus (VZV) is a human herpes virus that causes varicella as a primary infection and herpes zoster following reactivation of the virus from a latent state in trigeminal and spinal ganglia. In order to study the global pattern of VZV gene transcription, VZV microarrays using 75-base oligomers to 71 VZV open reading frames (ORFs) were designed and validated. The long-oligonucleotide approach maximizes the stringency of detection and polarity of gene expression. To optimize… CONTINUE READING

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