Transcriptionally silenced transgenes in maize are activated by three mutations defective in paramutation.

@article{McGinnis2006TranscriptionallyST,
  title={Transcriptionally silenced transgenes in maize are activated by three mutations defective in paramutation.},
  author={Karen M McGinnis and Catherine Springer and Yan Lin and Charles C. Carey and V. Katelyn Chandler},
  journal={Genetics},
  year={2006},
  volume={173 3},
  pages={1637-47}
}
Plants with mutations in one of three maize genes, mop1, rmr1, and rmr2, are defective in paramutation, an allele-specific interaction that leads to meiotically heritable chromatin changes. Experiments reported here demonstrate that these genes are required to maintain the transcriptional silencing of two different transgenes, suggesting that paramutation and transcriptional silencing of transgenes share mechanisms. We hypothesize that the transgenes are silenced through an RNA-directed… CONTINUE READING

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