Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

@article{Sugimoto2001TranscriptionallyAH,
  title={Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.},
  author={J. Sugimoto and N. Matsuura and Y. Kinjo and N. Takasu and T. Oda and Y. Jinno},
  journal={Genomics},
  year={2001},
  volume={72 2},
  pages={
          137-44
        }
}
Preceding the isolation of transcriptionally active HERV-K genes, expression status was examined by RT-PCR and sequence analysis of mRNA from various tissues. In addition to the detection of IDDMK(1,2)22/HERV-K18 expression in peripheral leukocytes, three novel members of the family, which are expressed in multiple tissues, were identified. The novel HERV-K genes (HGMW-approved symbols ERVK4 and ERVK5) were isolated from a BAC library using oligonucleotide probes and assigned by RH mapping to… Expand
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