Transcriptional synergy between melanoma antigen gene protein-A11 (MAGE-11) and p300 in androgen receptor signaling.

@article{Askew2010TranscriptionalSB,
  title={Transcriptional synergy between melanoma antigen gene protein-A11 (MAGE-11) and p300 in androgen receptor signaling.},
  author={Emily B. Askew and Suxia Bai and Amanda J. Blackwelder and Elizabeth M.C. Wilson},
  journal={The Journal of biological chemistry},
  year={2010},
  volume={285 28},
  pages={
          21824-36
        }
}
Androgen receptor (AR)-mediated gene regulation involves interactions with coregulatory proteins that include the melanoma antigen gene protein-A11 (MAGE-11). To understand the functional significance of sequence similarity between MAGE-11 and the adenovirus early protein E1A, we determined whether MAGE-11 contributes to AR transcriptional activity through an interaction with p300, a potent and ubiquitous transcriptional regulator. Here, we report that MAGE-11 interacts with the NH(2)-terminal… CONTINUE READING
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