Transcriptional response of skeletal muscle to a low-protein gestation diet in porcine offspring accumulates in growth- and cell cycle-regulating pathways.

@article{Oster2012TranscriptionalRO,
  title={Transcriptional response of skeletal muscle to a low-protein gestation diet in porcine offspring accumulates in growth- and cell cycle-regulating pathways.},
  author={Michael Oster and Eduard Murani and Cornelia C. Metges and Siriluck Ponsuksili and Klaus Wimmers},
  journal={Physiological genomics},
  year={2012},
  volume={44 16},
  pages={811-8}
}
Inadequate maternal protein supply during gestation represents an environmental factor that affects physiological signaling pathways with long-term consequences for growth, function, and structure of various tissues. Hypothesizing that the offspring's transcriptome is persistently altered by maternal diets, we used a porcine model to monitor the longitudinal expression changes in muscle to identify pathways relevant to fetal initiation of postnatal growth and development. German Landrace gilts… CONTINUE READING
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Low and excess dietary protein levels during gestation affect growth and compositional traits in gilts and impair offspring fetal growth

C Rehfeldt, I Lang, +9 authors C. Metges
J Anim Sci • 2011

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