Transcriptional repressor PRR5 directly regulates clock-output pathways

@article{Nakamichi2012TranscriptionalRP,
  title={Transcriptional repressor PRR5 directly regulates clock-output pathways},
  author={N. Nakamichi and T. Kiba and Mari Kamioka and T. Suzuki and T. Yamashino and T. Higashiyama and H. Sakakibara and T. Mizuno},
  journal={Proceedings of the National Academy of Sciences},
  year={2012},
  volume={109},
  pages={17123 - 17128}
}
The circadian clock is an endogenous time-keeping mechanism that enables organisms to adapt to external daily cycles. The clock coordinates biological activities with these cycles, mainly through genome-wide gene expression. However, the exact mechanism underlying regulation of circadian gene expression is poorly understood. Here we demonstrated that an Arabidopsis PSEUDO-RESPONSE REGULATOR 5 (PRR5), which acts in the clock genetic circuit, directly regulates expression timing of key… Expand
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