Transcriptional regulatory network analysis of developing human erythroid progenitors reveals patterns of coregulation and potential transcriptional regulators.

@article{Keller2006TranscriptionalRN,
  title={Transcriptional regulatory network analysis of developing human erythroid progenitors reveals patterns of coregulation and potential transcriptional regulators.},
  author={Margaret A. Keller and Sankar Addya and Rajanikanth Vadigepalli and Bubu A. Banini and K. Delgrosso and Hailu Huang and Saul Surrey},
  journal={Physiological genomics},
  year={2006},
  volume={28 1},
  pages={114-28}
}
Deciphering the molecular basis for human erythropoiesis should yield information benefiting studies of the hemoglobinopathies and other erythroid disorders. We used an in vitro erythroid differentiation system to study the developing red blood cell transcriptome derived from adult CD34+ hematopoietic progenitor cells. mRNA expression profiling was used to characterize developing erythroid cells at six time points during differentiation (days 1, 3, 5, 7, 9, and 11). Eleven thousand seven… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 38 extracted citations

Developmental transcriptome analysis of human erythropoiesis.

Human molecular genetics • 2014
View 6 Excerpts
Highly Influenced

Protein phosphatase 2A regulatory subunit B56β modulates erythroid differentiation.

Biochemical and biophysical research communications • 2016
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 63 references

Composite Module Analyst: a fitness-based tool for iden 127 ERYTHROID TRANSCRIPTIONAL REGULATORY NETWORK ANALYSIS Physiol Genomics

A Kel, T Konovalova, +3 authors E. Wingender
combinations. Bioinformatics • 2007
View 1 Excerpt

Similar Papers

Loading similar papers…