Transcriptional regulation of xyr1, encoding the main regulator of the xylanolytic and cellulolytic enzyme system in Hypocrea jecorina.

@article{MachAigner2008TranscriptionalRO,
  title={Transcriptional regulation of xyr1, encoding the main regulator of the xylanolytic and cellulolytic enzyme system in Hypocrea jecorina.},
  author={Astrid R. Mach-Aigner and Marion E. Pucher and Matthias G. Steiger and Gudrun E Bauer and Sonja J Preis and Robert L. Mach},
  journal={Applied and environmental microbiology},
  year={2008},
  volume={74 21},
  pages={6554-62}
}
In Hypocrea jecorina, Xyr1 (xylanase regulator 1) is the main transcription activator of hydrolase-encoding genes, such as xyn1, xyn2, bxl1, cbh1, cbh2, egl1, and bgl1. Even though Xyr1 mediates the induction signal for all these genes derived from various inducing carbon sources and compounds, xyr1 transcription itself is not inducible by any of these substances. However, cultivation on glucose as the carbon source provokes carbon catabolite repression of xyr1 transcription mediated by Cre1… CONTINUE READING