Transcriptional regulation of vascular endothelial growth factor expression in epithelial and stromal cells during mouse mammary gland development.

@article{Hovey2001TranscriptionalRO,
  title={Transcriptional regulation of vascular endothelial growth factor expression in epithelial and stromal cells during mouse mammary gland development.},
  author={Russell C. Hovey and Anita S. Goldhar and Judit Z. Baffi and Barbara K. Vonderhaar},
  journal={Molecular endocrinology},
  year={2001},
  volume={15 5},
  pages={819-31}
}
Accompanying changes in the development and function of the mammary gland is the establishment of a vascular network of critical importance for lactogenesis and tumorigenesis. A potent angiogenic and permeability factor that regulates vascular development in association with epithelial-stromal interactions is vascular endothelial growth factor (VEGF). Analysis of VEGF transcription by RT-PCR revealed mRNA for all three VEGF isoforms (VEGF120, 164, 188) within the mammary gland of nulliparous… CONTINUE READING

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