Transcriptional regulation of thyrotropin subunit genes by thyrotropin-releasing hormone and dopamine in pituitary cell culture.

@article{Shupnik1986TranscriptionalRO,
  title={Transcriptional regulation of thyrotropin subunit genes by thyrotropin-releasing hormone and dopamine in pituitary cell culture.},
  author={Margaret A. Shupnik and Susan L. Greenspan and Eli Chester Ridgway},
  journal={The Journal of biological chemistry},
  year={1986},
  volume={261 27},
  pages={12675-9}
}
Thyrotropin (TSH) is an anterior pituitary glycoprotein hormone which modulates thyroid hormone production by the thyroid gland. TSH and its two subunits, TSH beta and alpha-subunit, are in turn regulated by the thyroid hormones and several stimulatory and inhibitory factors produced by the hypothalamus. Hypothalamic hormones such as thyrotropin-releasing hormone (TRH) and dopamine have profound effects on TSH secretion and may also modulate TSH synthesis. We investigated the ability of these… CONTINUE READING
18 Citations
0 References
Similar Papers

Similar Papers

Loading similar papers…