Transcriptional regulation of the human <ce:italic>KiSS1</ce:italic> gene

@article{Mueller2011TranscriptionalRO,
  title={Transcriptional regulation of the human <ce:italic>KiSS1</ce:italic> gene},
  author={Johanna K. Mueller and Anja Dietzel and Alejandro Lomniczi and Alberto Loche and Sabine Heger},
  journal={Molecular and Cellular Endocrinology},
  year={2011},
  volume={342},
  pages={8-19}
}
Kisspeptin, the product of the KiSS1 gene, has emerged as a key component of the mechanism by which the hypothalamus controls puberty and reproductive development. It does so by stimulating the secretion of gonadotropin releasing hormone (GnRH). Little is known about the transcriptional control of the KiSS1 gene. Here we show that a set of proteins postulated to be upstream components of a hypothalamic network involved in controlling female puberty regulates KiSS1 transcriptional activity… CONTINUE READING
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